There are three difficulty settings:
On NORMAL difficulty, you will have a FAIL counter instead of lives, just so you know how poorly you did by the end. On CHALLENGE and EXTREME difficulties, you will have a LIVES counter which will reset the game if it hits 0.
This map is made for singleplayer but does work on multiplayer. However, please bear in mind that if one player picks an incorrect option, everyone in the game will receive the same penalty.